Dosing and side effects information

How will my loved one take NAMENDA?

If you think NAMENDA (memantine HCl) may be right for your loved one, talk to your doctor about how to begin therapy.


  • NAMENDA is recommended to be taken twice daily
  • NAMENDA can be taken with or without food
  • NAMENDA is available in tablet and liquid form

Therapy begins at a low dose (5 mg per day) of NAMENDA and is gradually increased until the recommended target dose (10 mg, twice daily) is reached. A recommended dosing schedule for beginning NAMENDA therapy is provided below.

Recommended NAMENDA dosing schedule:

  • Week 1: Starting on Day 1. Take one 5 mg tablet in the morning, each day.
  • Week 2: Starting on Day 8. Take one 5 mg tablet in the morning and one 5 mg tablet at night, each day.
  • Week 3: Starting on Day 15. Take one 10 mg tablet in the morning and one 5 mg tablet at night, each day.
  • Week 4: Starting on Day 22. Take one 10 mg tablet in the morning and one 10 mg tablet at night, each day.

A dosing pack guides patients through the first four weeks of therapy, while dosage is gradually increased.

Once the recommended target dose of NAMENDA (10 mg, twice daily) has been reached, people taking NAMENDA can continue with that daily regimen unless instructed otherwise by their doctors. (For patients with severe renal impairment, 5 mg twice daily is the recommended dose.) As with all types of prescription medications, do not stop taking NAMENDA without first talking to a doctor.

NAMENDA® (memantine hydrochloride) is indicated for the treatment of moderate to severe dementia of the Alzheimer's type. NAMENDA is available by prescription only.

There is no evidence that NAMENDA prevents or slows the underlying disease process in patients with Alzheimer's disease.


Who should NOT take NAMENDA?
NAMENDA should not be taken by anyone who is allergic (hypersensitive) to memantine, the active substance in NAMENDA, or who has had a bad reaction to NAMENDA or any of its ingredients.

What should be discussed with the healthcare provider before taking NAMENDA?
Before starting NAMENDA, talk to the healthcare provider about all of the patient's past and present medical conditions, including:

  • Seizure disorders
  • Difficulty passing urine
  • Liver, kidney or bladder problems

If the patient is taking other medications (including those without a prescription), ask the healthcare provider if NAMENDA is right for the patient.

  • Certain medications, changes in diet, or medical conditions may affect the amount of NAMENDA in the body and possibly increase side effects.

What are the possible side effects of NAMENDA?
The most common side effects associated with NAMENDA treatment are dizziness, confusion, headache, and constipation. This is not a complete list of side effects.

Please see full Prescribing Information.

For Healthcare Professionals

The information in this website is intended for healthcare professionals in the United States.

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